Episodes of status epilepticus in young adults: Etiologic factors, subtypes, and outcomes

Ozdilek B., MİDİ İ., AĞAN YILDIRIM K., BİNGÖL C. A.

EPILEPSY & BEHAVIOR, cilt.27, sa.2, ss.351-354, 2013 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Sayı: 2
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1016/j.yebeh.2013.02.023
  • Dergi Adı: EPILEPSY & BEHAVIOR
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.351-354
  • Anahtar Kelimeler: Status epilepticus, Etiology, Treatment and outcome, Young adult, CONVULSIVE STATUS EPILEPTICUS, REFRACTORY STATUS EPILEPTICUS, PREDICTORS, PROGNOSIS, EPIDEMIOLOGY, MORTALITY, CHILDREN, DEATH
  • Marmara Üniversitesi Adresli: Evet

Özet

The aim of this study was to evaluate the type, duration, etiology, treatment, and outcome of status epilepticus (SE) episodes, among patients aged 16-50 years. A total of 101 SE episodes in 88 young adult patients fulfilled our criteria. The mean age was 32 years. Status epilepticus episodes were most frequently observed in patients 21-30 years of age. A total of 53% of the patients were male, and 57% had pre-existing epilepsy. Seventy of the 101 episodes were convulsive SE. The most common etiology was withdrawal of or change in antiepileptic drugs (AEDs), seen in 31% of the SE episodes. This study included treatment of SE with traditional AEDs. Sixty-six episodes were treated successfully with intravenous infusion of 18-mg/kg phenytoin, and six episodes were treated with 10-mg/kg phenytoin. A total of 28% of the SE episodes remained refractory to first-line treatment, which was related to the duration of SE and mortality. The outcome was death in 14% of the patients due to underlying etiologies in the hospital. (C) 2013 Elsevier Inc. All rights reserved.