Association between occurrence of ossicular chain defect and osteoprotegerin gene expression in patients with chronic otitis media

Keskin, Serhan; Tatlipinar, Arzu; ATA, PINAR; Uzun, Selami; Kinal, Mustafa; Erkal, Burcin

doi:10.1007/s00405-019-05366-z

Association between occurrence of ossicular chain defect and osteoprotegerin gene expression in patients with chronic otitis media

Atıf İçin Kopyala

Keskin S., Tatlipinar A., ATA P., Uzun S., Kinal M. E., Erkal B.

EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, cilt.276, sa.5, ss.1321-1325, 2019 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 276 Sayı: 5
Basım Tarihi: 2019
Doi Numarası: 10.1007/s00405-019-05366-z
Dergi Adı: EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1321-1325
Marmara Üniversitesi Adresli: Evet

Özet

Objective Chronic otitis media (COM) is an important debilitating public problem causing hearing loss due to irreversible resorption of the ossicular chain. Activation of osteoprotegerin (OPG) during an acute attack of COM prevents bone resorption. The aim of the study was to investigate the role of OPG gene expression level on ossicular chain resorption in chronic otitis media.