Duration of Clinical Response After In-Office Steroid Injection for Vocal Fold Scar

Axiotakis Jr L. G. G., ENVER N., Kennedy E. L., Duncan K. A., Pitman M. J.

LARYNGOSCOPE, cilt.133, sa.9, ss.2333-2339, 2023 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 133 Sayı: 9
  • Basım Tarihi: 2023
  • Doi Numarası: 10.1002/lary.30539
  • Dergi Adı: LARYNGOSCOPE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, CINAHL, EMBASE, MEDLINE, MLA - Modern Language Association Database, Veterinary Science Database
  • Sayfa Sayıları: ss.2333-2339
  • Anahtar Kelimeler: laryngology, voice/dysphonia, vocal fold paralysis/paresis/motion impairment, OUTCOMES
  • Marmara Üniversitesi Adresli: Evet

Özet

Objective: To assess the duration of clinical response after in-office vocal fold steroid injection (VFSI) for vocal fold (VF) scar. Methods: Demographic and clinical data for in-office VFSI occurring from 2017 to 2020 were collected. Two Speech-Language Pathologists (SLPs) used perceptual evaluation of voice and functional scales to evaluate blinded voice and laryngovideostroboscopy (LVS) samples collected pre- and post-injection across multiple timepoints. Results: Blinded SLP ratings were used for 30 individual VFs undergoing initial injection in 18 patients. Persistent improvement in voice past 6 months was seen in 57% of patients after VFSI. Multiple measures of voice and amplitude, percent vibrating tissue, and closed phase predominance significantly improved at various follow-up timepoints on average. Conclusion: Accounting for patient heterogeneity and disease progression, in-office VFSI for VF scar is associated with sustained improvement in a subset of patients. Approximately half of patients can expect to experience a lasting improvement in voice. Future studies of larger scale are required to identify patient factors associated with long-term benefit.