BRAF V600 Mutation Profile of Metastatic Melanoma in the Thrace Region of Turkey

CAN N., TAŞTEKİN E., Deniz Yalta T., SÜT N., KORKMAZ S., USTA U., ...Daha Fazla

TURKISH JOURNAL OF PATHOLOGY, cilt.34, sa.2, ss.134-142, 2018 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 34 Sayı: 2
  • Basım Tarihi: 2018
  • Doi Numarası: 10.5146/tjpath.2018.01422
  • Dergi Adı: TURKISH JOURNAL OF PATHOLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.134-142
  • Anahtar Kelimeler: Malignant melanoma, BRAF mutation, Clinicopathological features, PRIMARY CUTANEOUS MELANOMA, DABRAFENIB, TRIAL, MEDICINE, FEATURES, CANCER, TUMORS, NRAS
  • Marmara Üniversitesi Adresli: Hayır

Özet

Objective: BRAF is the most common mutation in melanoma. The most common subtype is BRAF V600E, followed by V600K. Initially, the authors aimed to investigate whether clinicopathological features of melanoma are associated with BRAF mutations. We then aimed to present the relationships between the clinicopathological features and the mutated subtype (V600E vs V600K).