Comparison of soybean oil-based versus olive oil-based lipid emulsions in patients requiring parenteral nutrition Parenteral nütrisyonun gerektiği hastalardasoya yağı bazlı ile zeytinyağı bazlılipid emülsiyonları karşılaştırılması


TERZİOĞLU BEBİTOĞLU B., Ekinci O., Yılmaz Akyüz E., Özgültekin A., Türkmen F.

Goztepe Tip Dergisi, cilt.29, sa.2, ss.88-93, 2014 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 29 Sayı: 2
  • Basım Tarihi: 2014
  • Doi Numarası: 10.5222/j.goztepetrh.2014.088
  • Dergi Adı: Goztepe Tip Dergisi
  • Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.88-93
  • Anahtar Kelimeler: Albumin, Malnutrition, Olive oil-based fat emulsion, Prealbumin, Soybean oil-based fat emulsion
  • Marmara Üniversitesi Adresli: Hayır

Özet

Purpose: Malnutrition has a great importance and frequently encountered in hospitalized patients. Herein, the effects of olive oil-based and soybean oil-based fat emulsions on improvement of malnutrition status were compared together with evaluaten of biochemical parameters and hospital stay and mortality in hospitalized patients receiving parenteral nutrition (PN). Material and Methods: This retrospective study enrolled adult patients who were hospitalized longer than 24 hours, and considered as malnourished and supplied with parenteral nutrition were included in the study. Nutritional supplementation was applied by his/her clinician and they were followed up by hospital nutrition team without interfering the nutrition supplementation.Results: A total of 605 patients received soybean oil-based (n=408) and olive oil-based (n=197) lipid emulsions. The length of hospital stay was significantly longer in the soybean based oil-PN group than that of olive oil-based PN group (14.2±10.7 and 11.5±8.2 days, respectively; p<0.01). The mortality rates for soybean based oil-PN and olive oil-based PN group were 21.8 % and 22.8 %, respectively. The percent change in NRS-2002 score and body mass index were not different significantly. The percent change in albumin level was 7.0 % and 6.7 %, respectively without significant difference between groups. The percent change in prealbumin level in the soybean oil PN group were 3.4 % and was 15.2 % in olive oil PN group without significant difference. Conclusion: We found similar results between two groups in terms of serum albumin and prealbumin levels and mortality rates. Olive oil-based PN was associated with shorter duration of hospital stay than soybean oil-based PN.