Hydrophilic monomer and crosslinker effects on optical and chemical properties of hydrophobic intraocular lenses (IOLs)
MRS Communications, cilt.15, sa.4, ss.840-849, 2025 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 15 Sayı: 4
- Basım Tarihi: 2025
- Doi Numarası: 10.1557/s43579-025-00773-2
- Dergi Adı: MRS Communications
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Applied Science & Technology Source, Chemical Abstracts Core, Compendex, INSPEC
- Sayfa Sayıları: ss.840-849
- Anahtar Kelimeler: Biomaterial, Polymer, Polymerization
- Marmara Üniversitesi Adresli: Evet
Özet
An experimental study was conducted to reduce glistening and minimize posterior capsule opacification (PCO) in hydrophobic intraocular lenses (IOLs). This approach involved the copolymerization of hydrophilic 2-hydroxyethyl acrylate (HEA) at various concentrations with hydrophobic monomers, along with incorporating different amounts of ethylene glycol di-methacrylate (EGDMA) as a crosslinker to optimize the chemical, thermal, and optical properties. Sixteen IOL formulations were synthesized and systematically analyzed using equilibrium water content (EWC) measurements, glass-transition temperature (Tg) measurements, and optical evaluation. Optimizing the balance of hydrophilic monomer and crosslinker effectively eliminates glistening and mitigates PCO while maintaining the essential optical property of hydrophobic IOLs.