Lymphocyte proliferation in common variable immunodeficiency (CVID) patients by carboxyfluorescein succinimidyl ester (CFSE)

Izgi A., AKKOÇ T., Ogulur I., Tevetoglu A., AYDINER E., BARIŞ S., ...More

CLINICAL AND EXPERIMENTAL HEALTH SCIENCES, vol.1, no.3, pp.171-177, 2011 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 1 Issue: 3
  • Publication Date: 2011
  • Journal Name: CLINICAL AND EXPERIMENTAL HEALTH SCIENCES
  • Journal Indexes: Emerging Sources Citation Index (ESCI)
  • Page Numbers: pp.171-177
  • Keywords: CVID, CFSE, Lymphocytes proliferation, T lymphocyte isolation, B lymphocyte isolation
  • Marmara University Affiliated: Yes

Abstract

Objective: Common variable immunodeficiency (CVID) is a heterogeneous disease in the group of predominantly antibody deficiencies, which is defined by hypogammaglobulinemia and normal or low level of B cells, and characterized by increased susceptibility to recurrent bacterial infections, autoimmune disorders, and malignancies. In this study, we aimed to investigate the proliferation of the B and T lymphocytes in patients with CVID.