Anti-inflammatory effect of D-pinitol isolated from the leaves of Colutea cilicica Boiss et Bal. on K562 cells

Eser F., Altundag E. M., GEDİK G., DEMİRTAŞ İ., ÖNAL A., SELVİ B.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.42, sa.4, ss.445-450, 2017 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 42 Sayı: 4
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1515/tjb-2016-0120
  • Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.445-450
  • Anahtar Kelimeler: Anti-inflammatory activity, K562, Colutea cilicica Boiss et Bal., Isolation, D-pinitol, FACTOR-KAPPA-B, INHIBITION, ACTIVATION, APOPTOSIS, PRODUCTS, INVASION
  • Marmara Üniversitesi Adresli: Evet

Özet

Aim: D-pinitol, a natural compound has shown various biological and pharmacological effects. Last studies are focused on the determination of its further pharmacological activities including mainly biological activity. Therefore, isolation of D-pinitol from the leaves of Colutea cilicica Boiss et Bal. and investigation of its apoptotic and anti-inflammatory activity on K562 cell lines were aimed in the concept of the study.