Sucralose enhances GLP-1 release and lowers blood glucose in the presence of carbohydrate in healthy subjects but not in patients with type 2 diabetes

Temizkan S., Deyneli O., Yasar M., Arpa M., Gunes M., Yazici D., ...Daha Fazla

EUROPEAN JOURNAL OF CLINICAL NUTRITION, cilt.69, sa.2, ss.162-166, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 69 Sayı: 2
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1038/ejcn.2014.208
  • Dergi Adı: EUROPEAN JOURNAL OF CLINICAL NUTRITION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.162-166
  • Marmara Üniversitesi Adresli: Evet

Özet

BACKGROUND/OBJECTIVE: Artificial sweeteners were thought to be metabolically inactive, but after demonstrating that the gustatory mechanism was also localized in the small intestine, suspicions about the metabolic effects of artificial sweeteners have emerged. The objective of this study was to determine the effect of artificial sweeteners (aspartame and sucralose) on blood glucose, insulin, c-peptide and glucagon-like peptide-1 (GLP-1) levels.