Cardiac effects of granisetron in a prospective crossover randomized dose comparison trial.

Cakir F. B. , Yapar O., Canpolat C., Akalin F. , Berrak S. G.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, vol.20, no.10, pp.2451-7, 2012 (Journal Indexed in SCI Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 10
  • Publication Date: 2012
  • Doi Number: 10.1007/s00520-011-1376-5
  • Title of Journal : Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
  • Page Numbers: pp.2451-7
  • Keywords: Granisetron, Cardiac side effects, Creatine phosphokinase, MODERATELY EMETOGENIC CHEMOTHERAPY, ISCHEMIC MYOCARDIAL INJURY, DOUBLE-BLIND, INTRAVENOUS DOLASETRON, RECEIVING CHEMOTHERAPY, RECEPTOR ANTAGONISTS, DELAYED NAUSEA, TROPONIN-T, CHILDREN, ONDANSETRON

Abstract

Cardiac side effects of granisetron have been studied mostly in adult patients that are using cardiotoxic chemotherapeutics. There is limited evidence in pediatric age group and no information in pediatric oncology patients with non-cardiotoxic chemotherapeutics.