An unusual native tricuspid valve endocarditis caused by Candida colliculosa

Kaygusuz I., Mulazimoglu L., Cerikcioglu N., Toprak A., Oktay A., Korten V.

CLINICAL MICROBIOLOGY AND INFECTION, vol.9, no.4, pp.319-322, 2003 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 9 Issue: 4
  • Publication Date: 2003
  • Doi Number: 10.1046/j.1469-0691.2003.00511.x
  • Journal Name: CLINICAL MICROBIOLOGY AND INFECTION
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.319-322
  • Keywords: Candida spp., fungal endocarditis, native-valve endocarditis, FUNGAL ENDOCARDITIS, YEASTS
  • Marmara University Affiliated: Yes

Abstract

Candida colliculosa , which grew in blood cultures of a 71-year-old retired man with fever of unknown origin that had lasted for 7 months, in conjunction with transthoracic echocardiography, demonstrating a 20-mm vegetation, superior to the tricuspid valve, herniating into the right atrial cavity. The finding led to the diagnosis of fungal endocarditis. Fluconazole, 600 mg daily, was commenced for 8 days; followed by amphotericin B, 1 mg/kg daily. On the fourth day of the amphotericin B treatment, the patient underwent replacement of the infected tricuspid valve. Even though the initial postoperative period was relatively uncomplicated, the patient died after a gross aspiration on the 67th day of his hospital stay, despite aggressive cardiovascular support and antimicrobial therapy. This is the first report of a native tricuspid valve fungal endocarditis due to C. colliculosa or Torulaspora delbrueckii , which is not known to be a human pathogen.