Efficacy and Safety of Percutaneous Microwave Ablation for Liver Tumors Using an Antenna with Anti-phase Technology Offering Ultraspherical Ablation


Arık E., Taydaş O., Dertli T., Sevinç Ö. F., Topaloğlu Ö. F., Özdemir M., ...Daha Fazla

European Conference on Interventional Oncology, Rotterdam, Hollanda, 13 - 16 Nisan 2025, ss.118, (Özet Bildiri)

  • Yayın Türü: Bildiri / Özet Bildiri
  • Doi Numarası: 10.1007/s00270-025-04024-8
  • Basıldığı Şehir: Rotterdam
  • Basıldığı Ülke: Hollanda
  • Sayfa Sayıları: ss.118
  • Marmara Üniversitesi Adresli: Evet

Özet

Purpose:

Anti-phase technology, a novel advancement in microwave antennas for percutaneous liver ablations, forms

more spherical ablation zones. This study aimed to evaluate the efficacy and safety of microwave ablation

(MWA) treatment for liver tumors using a microwave antenna equipped with anti-phase technology.

Material and methods:

The study included 92 patients (133 lesions) treated with MWA for hepatocellular carcinoma (HCC) or liver

metastases. Of these, nine patients had HCC, and 83 had metastases (46 colorectal and 37 non-colorectal

metastases). Retrospective analysis was conducted on patients’ age, sex, pre- and post-procedural laboratory

values (white blood cell count, neutrophil-to-lymphocyte ratio), tumor dimensions (pre-procedure and postprocedure

day 1 and months 1, 3, and 6), details of the MWA procedure (duration, power output), procedurerelated

complications, and local progression/recurrence during follow-up.

Results:

The technical success rate of MWA was 100%. Ablations were performed at a median power output of 80

watts (range: 50–100), and the mean ablation duration was 5.2±2.1 minutes. Follow-up imaging revealed an

ablation zone diameter-to-tumor diameter ratio of 1.63±0.3. Major complications occurred in three patients

(3.2%). Minor complications were observed in 29 patients (31.5%). The median disease-free survival time was

25 months (95% confidence interval: 21–27). Tumor size was identified as an independent risk factor for local

progression (p=0.012).

Conclusion:

This study represents the longest follow-up duration and the largest patient cohort for the MWA treatment of

liver tumors using anti-phase technology. The