CLINICAL ENDOCRINOLOGY, cilt.57, sa.5, ss.621-628, 2002 (SCI-Expanded)
OBJECTIVE The efficacy and the effective dose of levothyroxine suppressive therapy in the treatment of benign thyroid nodules are controversial. In this study, we aimed to determine the response of solitary thyroid nodules to low- or high-level TSH suppression in a placebo-controlled, randomized crossover trial.