Effect of low- and high-dose levothyroxine on thyroid nodule volume: a crossover placebo-controlled trial

Koc M. , Ersoz H., Akpinar I., Gogas-Yavuz D. , Deynell O., Akalin S.

CLINICAL ENDOCRINOLOGY, cilt.57, sa.5, ss.621-628, 2002 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 57 Konu: 5
  • Basım Tarihi: 2002
  • Doi Numarası: 10.1046/j.1365-2265.2002.01650.x
  • Sayfa Sayıları: ss.621-628


OBJECTIVE The efficacy and the effective dose of levothyroxine suppressive therapy in the treatment of benign thyroid nodules are controversial. In this study, we aimed to determine the response of solitary thyroid nodules to low- or high-level TSH suppression in a placebo-controlled, randomized crossover trial.