Tissue factor activities of streptozotocin induced diabetic rat tissues and the effect of peanut consumption

Emekli-Alturfan E. I., Kasikci E., Yarat A.

DIABETES-METABOLISM RESEARCH AND REVIEWS, vol.23, no.8, pp.653-658, 2007 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 23 Issue: 8
  • Publication Date: 2007
  • Doi Number: 10.1002/dmrr.757
  • Journal Name: DIABETES-METABOLISM RESEARCH AND REVIEWS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.653-658
  • Marmara University Affiliated: Yes

Abstract

Background Tissue factor (TF) is considered to be a major regulator of normal haemostasis and thrombosis. Circulating TF activity is suggested to be associated with diabetes mellitus. Various tissues and body fluids have TF activity. The aim of the present study was to investigate the TF activity of streptozotocin (STZ) induced diabetic rat tissues. Peanut consumption is reported to be associated with decreased risk of type 2 diabetes. Therefore, the effect of peanut consumption on the TF activity of STZ induced diabetic rat tissues, and haemostatic parameters such as protrombin time (PT), activated partial thromboplastin time (APTT) and fibrinogen levels were determined.