Glucocorticoid deficiency causes transcriptional and post-transcriptional reprogramming of glutamine metabolism


Weger M., Weger B. D. , Goerling B., Poschet G., Yildiz M., Hell R., et al.

EBIOMEDICINE, cilt.36, ss.376-389, 2018 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 36
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1016/j.ebiom.2018.09.024
  • Dergi Adı: EBIOMEDICINE
  • Sayfa Sayısı: ss.376-389

Özet

Background: Deficient glucocorticoid biosynthesis leading to adrenal insufficiency is life-threatening and is associated with significant co-morbidities. The affected pathways underlying the pathophysiology of co-morbidities due to glucocorticoid deficiency remain poorly understood and require further investigation.