Silymarin, the antioxidant component of Silybum marianum, protects against burn-induced oxidative skin injury

Toklu H. Z., Tunah-Akbay T., Erkani G., Yuksel M., Ercan F., Sener G.

Burns, cilt.33, sa.7, ss.908-916, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 33 Sayı: 7
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1016/j.burns.2006.10.407
  • Dergi Adı: Burns
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.908-916
  • Anahtar Kelimeler: Silymarin, burn skin, thermal, oxidative, injury, THERMAL-INJURY, ORGAN DAMAGE, RAT MODEL, LIPID-PEROXIDATION, REACTIVE OXYGEN, STRESS, INHIBITION, MELATONIN, BLOOD, STAGE
  • Marmara Üniversitesi Adresli: Evet

Özet

Background: Despite recent advances, severe burn is one of the most common problems faced in the emergency room. Major thermal injury induces the activation of an inflammatory cascade resulting in local tissue damage, to contribute to the development of subsequent damage of multiple organs distant from the original burn wound.