Association between bactericidal/permeability increasing protein (BPI) gene polymorphism (Lys216Glu) and inflammatory bowel disease


Akin H., Tahan G., Ture F., EREN F. , ATUĞ Ö. , Tahan V., et al.

JOURNAL OF CROHNS & COLITIS, cilt.5, ss.14-18, 2011 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 5 Konu: 1
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1016/j.crohns.2010.08.008
  • Dergi Adı: JOURNAL OF CROHNS & COLITIS
  • Sayfa Sayısı: ss.14-18

Özet

Background: Increasing Increasing evidence suggests that innate immune system may have a key role in the pathogenesis of the inflammatory bowel disease (IBD). Bactericidal/permeability increasing protein (BPI) has an important role in the recognition and neutralization of gram-negative bacteria by host innate immune system. The polymorphism on BPI gene called Lys216Glu is on the suspected list of IBD pathogenesis.