Association between bactericidal/permeability increasing protein (BPI) gene polymorphism (Lys216Glu) and inflammatory bowel disease

Akin H., Tahan G., Ture F., EREN F., ATUĞ Ö., Tahan V., ...Daha Fazla

JOURNAL OF CROHNS & COLITIS, cilt.5, sa.1, ss.14-18, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 5 Sayı: 1
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1016/j.crohns.2010.08.008
  • Dergi Adı: JOURNAL OF CROHNS & COLITIS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.14-18
  • Marmara Üniversitesi Adresli: Evet

Özet

Background: Increasing Increasing evidence suggests that innate immune system may have a key role in the pathogenesis of the inflammatory bowel disease (IBD). Bactericidal/permeability increasing protein (BPI) has an important role in the recognition and neutralization of gram-negative bacteria by host innate immune system. The polymorphism on BPI gene called Lys216Glu is on the suspected list of IBD pathogenesis.