Plasma Neuropeptide Y Levels in Medication Naive Adolescents with Major Depressive Disorder

Gulec M. Y., Ozalmete O. A., Ozturk M., Gulec H., Sayar K., KÖSE A.

KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY, vol.20, no.2, pp.132-138, 2010 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 2
  • Publication Date: 2010
  • Doi Number: 10.1080/10177833.2010.11790647
  • Journal Name: KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.132-138
  • Keywords: Neuropeptide Y, emotional regulation, anxiety, depression, adolescents, ALCOHOL DEPENDENCE, SUICIDAL PATIENTS, PEPTIDE-YY, NPY, STRESS, IMMUNOREACTIVITY, HYPOTHALAMUS, INVOLVEMENT, INVENTORY, NEURONS
  • Marmara University Affiliated: No

Abstract

Objective: Neuropeptide Y (NPY) has been implicated in pathophysiology of anxiety and depression. It was proposed that NPY counteracts corticotropin-releasing factor-mediated stress effects to maintain emotional regulation. We investigated NPY concentrations in a sample of first episode medication-naive adolescent patients with MDD with regards to their history of suicide attempts.