Salivary levels of antimicrobial peptides Hnp 1-3, Ll-37 and S100 in Behcet's disease.

MUMCU G., Cimilli H., Karacayli U., Inanc N., Ture-Ozdemir F., Eksioglu-Demiralp E., ...Daha Fazla

Archives of oral biology, cilt.57, sa.6, ss.642-6, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 57 Sayı: 6
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1016/j.archoralbio.2011.11.003
  • Dergi Adı: Archives of oral biology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.642-6
  • Anahtar Kelimeler: Behget disease, Saliva and HNP 1-3, EXPRESSION, NEUTROPHILS, CARIES, CELLS, PATHOGENESIS, ASSOCIATION, ACTIVATION, SEVERITY, PROTEINS, HEALTH
  • Marmara Üniversitesi Adresli: Evet

Özet

Background: Oral ulcer is the cardinal clinical sign and increased neutrophilic activity is a part of the pathogenesis in Behcet's disease (BD). Saliva, as a part of the innate immune response, contains antimicrobial peptides (AMPs) that are derived from both oral epithelial cells and neutrophils. The aim of this study was to investigate the associations between salivary levels of AMPs HNP 1-3, LL-37 and S100 and disease course in patients with Behcet's disease (BD).