The effect of oestrogen and testosterone on the urethral seam of the developing male mouse genital tubercle

YÜCEL S., Cavalcanti A., Desouza A., Wang Z., Baskin L.

BJU INTERNATIONAL, vol.92, no.9, pp.1016-1021, 2003 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 92 Issue: 9
  • Publication Date: 2003
  • Doi Number: 10.1111/j.1464-410x.2003.04511.x
  • Journal Name: BJU INTERNATIONAL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1016-1021
  • Keywords: urethra, development, seam area, oestrogen, testosterone, mouse, hypospadias, endocrine disrupters, ANDROGEN RECEPTORS, HYPOSPADIAS, ABNORMALITIES, EXPRESSION, ONTOGENY, TRENDS
  • Marmara University Affiliated: No

Abstract

To describe the effects of exogenous oestrogens and androgens on urethral formation in the mouse, as the development of the mouse and human urethra have significant similarities, and understanding normal male urethral development may help to identify the causes of abnormal development, e.g. hypospadias.