Reflections of upper extremity performance in idiopathic pulmonary fibrosis on exercise capacity, clinical status, and quality of life
Sarcoidosis Vasculitis and Diffuse Lung Diseases, cilt.43, sa.3, 2026 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 43 Sayı: 3
- Basım Tarihi: 2026
- Doi Numarası: 10.36141/svdld.2026.18847
- Dergi Adı: Sarcoidosis Vasculitis and Diffuse Lung Diseases
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE
- Anahtar Kelimeler: 6-minute pegboard and ring test, exercise capacity, exercise tolerance, idiopathic pulmonary fibrosis, unsupported upper extremity exercise test, upper extremity
- Marmara Üniversitesi Adresli: Evet
Özet
Background and aim: Clinical assessments in idiopathic pulmonary fibrosis (IPF) typically emphasize lower extremities; however, upper extremity performance may also influence clinical status, daily functioning, and quality of life. This study aimed to examine the relationship between upper extremity performance and exercise capacity, clinical status, and quality of life. Methods: IPF patients underwent 6-minute pegboard and ring test (6PBRT), Unsupported Upper Extremity Exercise Test (UULEX), 6-Minute Walk Test (6MWT), 1-Minute Sit-to-Stand Test (1MSTST), Modified Medical Research Council Dyspnea Scale (mMRC), Fatigue Severity Scale (FSS), London Chest Activities of Daily Living Scale (LCADL), and St. George Respiratory Questionnaire (SGRQ). Results: Moderate correlation was found between 6PBRT and 6MWT (r=0.516, p=0.017), 1MSTST (r=0.612, p=0.003), and UULEX (r=0.614, p=0.003). Negative correlations were observed between 6PBRT and mMRC (r=-0.482, p=0.027), GAP Index (r=-0.453, p=0.039), and LCADL-Leisure (r=-0.519, p=0.016). In an exploratory multiple linear regression analysis, 6MWT distance and GAP Index together explained 30% of the variance in 6PBRT performance (R2=0.303, p=0.039). Additionally, UULEX was negatively correlated with mMRC, FSS, LCADL, and SGRQ scores. Conclusions: The 6PBRT showed moderate associations with lower extremity performance and selected clinical measures in patients with IPF. These findings provide preliminary support for the inclusion of 6PBRT and UULEX as complementary tools in a comprehensive functional assessment; however, the results should be interpreted cautiously given the exploratory nature of the analysis.