Comparison of the protective effects of various antiulcer agents alone or in combination on indomethacin-induced gastric ulcers in rats

Izzettin F. V., SANCAR M., OKUYAN B., Apikoglu-Rabus S., Cevikbas U.

EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY, cilt.64, sa.4, ss.339-343, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 64 Sayı: 4
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1016/j.etp.2010.09.007
  • Dergi Adı: EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
  • Sayfa Sayıları: ss.339-343
  • Anahtar Kelimeler: Indomethacin-induced gastric ulcer, Omeprazole, Misoprostol, Ranitidine, Bismuth, Rat, NONSTEROIDAL ANTIINFLAMMATORY DRUGS, OMEPRAZOLE, MISOPROSTOL, PREVENTION, CIMETIDINE, SUCRALFATE, ASPIRIN, THERAPY
  • Marmara Üniversitesi Adresli: Evet

Özet

The aim of this study which was structured with the objective of determination of the optimum protective therapy against the long term NSAID therapy-induced ulcers was to compare the gastro-protective effects of various antiulcer drugs (ranitidine, omeprazole, bismuth and misoprostol)alone or in combination with each other in different doses on indomethacin-induced gastric ulcers in rats.