Botulinum toxin and intractable trigeminal neuralgia


Turk U., Ilhan S., Alp R., Sur H.

CLINICAL NEUROPHARMACOLOGY, cilt.28, sa.4, ss.161-162, 2005 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 28 Sayı: 4
  • Basım Tarihi: 2005
  • Dergi Adı: CLINICAL NEUROPHARMACOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.161-162
  • Anahtar Kelimeler: trigeminal neuralgia, treatment, botulinum toxin
  • Marmara Üniversitesi Adresli: Hayır

Özet

The effects of botulinum toxin have been demonstrated in pain syndromes such as migraine, tension headache, and postherpetic neuralgia. With this background data in hand, the authors planned a randomized, open-ended study to investigate the efficacy of botulinum injections in cases of refractory trigeminal neuralgia. In 8 patients with trigeminal neuralgia, 100 U botulinum toxin was injected into the region of the zygomatic arch. The results of their statistical analyses demonstrated that the medication can be effective in treating trigeminal neuralgia. The patients did not develop any significant adverse effects. Botulinum toxin can be used in the treatment of refractory trigeminal neuralgia.