Dental Imaging using Laminar Optical Tomography and Micro CT

Long F., ÖZTÜRK M. S., Intes X., Kotha S.

Conference on Multimodal Biomedical Imaging IX, San-Francisco, Kostarika, 1 - 02 Şubat 2014, cilt.8937 identifier identifier

  • Yayın Türü: Bildiri / Tam Metin Bildiri
  • Cilt numarası: 8937
  • Doi Numarası: 10.1117/12.2037766
  • Basıldığı Şehir: San-Francisco
  • Basıldığı Ülke: Kostarika
  • Anahtar Kelimeler: Dental Imaging, Laminar Optical Tomography, Micro-CT, Teeth, Image Registration, Molecular Imaging, Mesoscopic Fluorescence Molecular Tomography, Monte Carlo, Fluorescence, FLUORESCENCE MOLECULAR TOMOGRAPHY, TURBID MEDIA
  • Marmara Üniversitesi Adresli: Hayır

Özet

Dental lesions located in the pulp are quite difficult to identify based on anatomical contrast, and, hence, to diagnose using traditional imaging methods such as dental CT. However, such lesions could lead to functional and/or molecular optical contrast. Herein, we report on the preliminary investigation of using Laminar Optical Tomography (LOT) to image the pulp and root canals in teeth. LOT is a non-contact, high resolution, molecular and functional mesoscopic optical imaging modality. To investigate the potential of LOT for dental imaging, we injected an optical dye into ex vivo teeth samples and imaged them using LOT and micro-CT simultaneously. A rigid image registration between the LOT and micro-CT reconstruction was obtained, validating the potential of LOT to image molecular optical contrast deep in the teeth with accuracy, non-invasively. We demonstrate that LOT can retrieve the 3D bio-distribution of molecular probes at depths up to 2mm with a resolution of several hundred microns in teeth.