Renal Cell Carcinoma With Tumor Thrombus Extending Into the Inferior Vena Cava and the Right Atrium Demonstrated by68Ga-DOTATATE PET/CT

Filizoglu N., ÖZGÜVEN S.

Clinical Nuclear Medicine, vol.49, no.11, 2024 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 49 Issue: 11
  • Publication Date: 2024
  • Doi Number: 10.1097/rlu.0000000000005487
  • Journal Name: Clinical Nuclear Medicine
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE
  • Keywords: 68Ga-DOTATATE, inferior vena cava, PET/CT, renal cell carcinoma, tumor thrombus
  • Marmara University Affiliated: Yes

Abstract

Approximately 10% of all renal cell carcinoma (RCC) patients develop a venous tumor thrombus, a major negative prognostic factor. Surgical excision is commonly required for RCC patients with tumor thrombus. Accurate preoperative diagnosis and assessment of tumor thrombus level is vital because the level of thrombus may influence treatment decisions. MRI, contrast-enhanced CT, 18F-FDG PET/CT, and 68Ga-PSMA PET/CT have been used to diagnose and evaluate the extent of tumor thrombus in RCC. However, no case of RCC with inferior vena cava tumor thrombus showing 68Ga-DOTATATE uptake has been reported yet. Herein, we report a case of metastatic RCC with tumor thrombus in the inferior vena cava on 68Ga-DOTATATE PET/CT.