Cyclooxygenase-2 expression in primary and recurrent pterygium


ADIGÜZEL U., Karabacak T., SARI A. A., öz ö., CİNEL Z. L.

EUROPEAN JOURNAL OF OPHTHALMOLOGY, cilt.17, sa.6, ss.879-884, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 6
  • Basım Tarihi: 2007
  • Dergi Adı: EUROPEAN JOURNAL OF OPHTHALMOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.879-884
  • Anahtar Kelimeler: pterygium, primary, recurrent, cyclooxygenase-2, SQUAMOUS-CELL CARCINOMA, INDUCED SKIN TUMORS, MITOMYCIN-C, COX-2 EXPRESSION, CELECOXIB, INHIBITOR, MURINE, CORNEA
  • Marmara Üniversitesi Adresli: Hayır

Özet

PURPOSE. Pterygium is a proliferative, inflammatory, and invasive ocular surface disease associated with excessive ultraviolet radiation exposure and has several tumor-like characteristics. Cyclooxygenase-2 (COX-2) is an inducible enzyme and recently increased expression of the enzyme was found in many cancers and premalign lesions. This study was conducted to identify the COX-2 expression in pterygium tissues.