Akademik Veri Yönetim Sistemi
Applications of Chemistry in Nanosciences and Biomaterials Engineering NanoBioMat 2025 – Winter Edition, Bucuresti, Romanya, 26 - 28 Kasım 2025, ss.80-82, (Özet Bildiri)
The paradigm in nanotechnology is shifting towards sustainable and eco-friendly synthesis methods to circumvent the environmental and economic drawbacks of conventional physicochemical approaches. Conventional chemical and physical methods frequently utilise hazardous reagents, consume substantial energy, and produce toxic byproducts [1]. This study presents a facile, cost-effective, and green strategy for the synthesis of copper (Cu), zinc (Zn), and silver (Ag) nanoparticles using an extract of highbush blueberry, Vaccinium corymbosum L. (VC). The fruit was selected as a bio-reductant and stabiliser due to its exceptionally rich profile of natural antioxidants, including anthocyanins, flavonols, and phenolic acids, which are capable of reducing metal ions and capping the nanoparticles to ensure colloidal stability [2,3]. A straightforward, one-pot synthesis method was employed where blueberry extract was reacted with solutions of metal salts individually for single nanoparticles, in pairs for binary combinations, and all together for the ternary nanoparticles. The formation of nanoparticles was confirmed by visual observation of characteristic color changes and subsequent UV-visible spectroscopy, which detected distinct absorption profiles for each type of nanoparticle. The study's core methodology centred on a systematic comparison of the antioxidant capacities of all synthesized nano-formulations. This was quantitatively assessed using standard in vitro assays, including the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging and FolinCiocalteu assay. The results indicate that the complex interaction between different metals in a composite nanoparticle stabilized with phytochemicals from blueberry extract creates an antioxidant material. The successful synthesis and demonstrated potent antioxidant activity of these biogenic nanoparticles pave the way for their potential application in diverse fields. The VC-AgNPs, with their strong radical scavenging properties, are proposed as promising candidates for topical wound healing formulations and as active components in cosmetic products designed to mitigate oxidative stress. The VC-ZnNPs and VC-CuNPs hold significant potential in agri-food sectors as nano-fertilizers or antimicrobial coatings for food preservation, leveraging their dual role as essential micronutrients and antioxidants. This study demonstrates the efficacy of Vaccinium corymbosum extract in facilitating the green synthesis of multifunctional metal nanoparticles with antioxidant properties, supporting their prospective use as natural antioxidants in biomedical and industrial applications [4].