The Role of Acyclovir in the Treatment of Herpes zoster Virus Infections in Immunocompromised Children

Demir S., KEPENEKLİ KADAYİFCİ E., Karaaslan A., Atici S., Akkoc G., YAKUT N., ...Daha Fazla

JOURNAL OF PEDIATRIC INFECTION, cilt.9, sa.4, ss.142-146, 2015 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 9 Sayı: 4
  • Basım Tarihi: 2015
  • Doi Numarası: 10.5152/ced.2015.2147
  • Dergi Adı: JOURNAL OF PEDIATRIC INFECTION
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.142-146
  • Anahtar Kelimeler: Varicella, herpes zoster, immune deficiency, acyclovir, HUMAN-LEUKOCYTE INTERFERON, CONTROLLED-TRIAL, VARICELLA, TRANSPLANTATION, DISSEMINATION, CHICKENPOX, SIMPLEX, CANCER
  • Marmara Üniversitesi Adresli: Evet

Özet

Objective: Varicella and herpes zoster are infectious diseases caused by varicella-zoster virus (VZV) and are generally not serious diseases in immunocompetent patients. However, patients with impaired cellular immunity because of chemotherapy, immune suppressive agent, HIV infection, and primary immune deficiency syndromes have tendency toward causing infections with VZV; also, VZV infections may be more severe with complications in these patient groups. Acyclovir is the drug of choice for treatment of both illnesses. Herein, we aim to describe the characteristics of VZV infections and the role of acyclovir in the treatment of immunocompromised children for these infections.