A novel approach in allergen-specific immunotherapy: Combination of sublingual and subcutaneous routes

Keles S., Karakoc-Aydiner E., Ozen A. O., Izgi A. G., Tevetoglu A., AKKOÇ T., ...Daha Fazla

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, cilt.128, sa.4, ss.808-822, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 128 Sayı: 4
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1016/j.jaci.2011.04.033
  • Dergi Adı: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.808-822
  • Anahtar Kelimeler: Children, cytokine, Der p 1, subcutaneous immunotherapy, sublingual immunotherapy, GRASS-POLLEN IMMUNOTHERAPY, DOUBLE-DUMMY, DOUBLE-BLIND, BEE VENOM, ASTHMA, RESPONSES, EFFICACY, RHINITIS, IGG, MECHANISMS
  • Marmara Üniversitesi Adresli: Evet

Özet

Background: Subcutaneous allergen-specific immunotherapy (SIT) has an early onset of action, whereas repeated injections and safety concerns have limited its use in the pediatric age group. Meanwhile, the improved safety profile of the sublingual route has been accepted as an alternative despite its relatively late onset of action.