A novel approach in allergen-specific immunotherapy: Combination of sublingual and subcutaneous routes


Keles S., Karakoc-Aydiner E. , Ozen A. O. , Izgi A. G. , Tevetoglu A., AKKOÇ T. , ...More

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, vol.128, no.4, pp.808-822, 2011 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 128 Issue: 4
  • Publication Date: 2011
  • Doi Number: 10.1016/j.jaci.2011.04.033
  • Title of Journal : JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
  • Page Numbers: pp.808-822

Abstract

Background: Subcutaneous allergen-specific immunotherapy (SIT) has an early onset of action, whereas repeated injections and safety concerns have limited its use in the pediatric age group. Meanwhile, the improved safety profile of the sublingual route has been accepted as an alternative despite its relatively late onset of action.