Akademik Veri Yönetim Sistemi
Epilepsy and Behavior, cilt.167, 2025 (SCI-Expanded)
Background: Anxiety, depression, and stigma can significantly affect the quality of life of people with epilepsy. This study was carried out to determine the relationship between these factors. Method: The study was conducted with 325 people with epilepsy admitted to the neurology outpatient clinic of a training and research hospital in Istanbul, Türkiye. Data were collected using a General Information Form, the Depression in Neurological Disorders Scale-Epilepsy (NDDI-E), Generalized Anxiety Disorder-7 Scale (GAD-7), Epilepsy Self-Stigma Scale (ESSS), and Quality of Life in Epilepsy Scale (QOLIE-31). Data were analyzed using the Student's t-test, one-way ANOVA, Pearson correlation, and multiple linear regression test. Results: Of the included patients, 60.9 % were female, 61.5 % were married, and 84.3 % had generalized seizures. The mean anxiety score was 16.80 ± 6.13, and 13.5 % of patients had mild anxiety, 27.7 % had moderate anxiety, and 58.8 % had severe anxiety. The mean depression score was 14.07 ± 3.58, and 39.7 % of the patients were at risk for depression. The mean total score for stigma was 14.29 ± 5.67, and the mean total score of the quality of life scale was 47.54 ± 11.36. Quality of life decreased with increasing levels of depression (r = -0.418; p < 0.001), anxiety (r = -0.292; p < 0.001), and stigma (r = -0.224; p < 0.001). Depression, anxiety, stigma, and seizure frequency explained 25 % of the total variance in quality of life. Conclusion: There was a negative correlation between anxiety, depression, stigma, and quality of life. These factors, as well as seizure frequency, were statistically significant predictors of quality of life in people with epilepsy.