Antidepressant-Like Effects of Ceftriaxone in Chronic Unpredictable Mild Stress Model in Rats: The Importance of Reuptake Time of Glutamate

Binnetoglu, Damla; ARICIOĞLU, FEYZA; ÖZCAN, Halil; OKKAY, Ufuk; HACIMÜFTÜOĞLU, Ahmet

doi:10.33808/clinexphealthsci.613963

Antidepressant-Like Effects of Ceftriaxone in Chronic Unpredictable Mild Stress Model in Rats: The Importance of Reuptake Time of Glutamate

Atıf İçin Kopyala

Binnetoglu D., ARICIOĞLU F., ÖZCAN H., OKKAY U., HACIMÜFTÜOĞLU A.

CLINICAL AND EXPERIMENTAL HEALTH SCIENCES, cilt.9, sa.4, ss.294-299, 2019 (ESCI)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 9 Sayı: 4
Basım Tarihi: 2019
Doi Numarası: 10.33808/clinexphealthsci.613963
Dergi Adı: CLINICAL AND EXPERIMENTAL HEALTH SCIENCES
Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
Sayfa Sayıları: ss.294-299
Marmara Üniversitesi Adresli: Evet

Özet

Objective: We aimed to indicate the relationship between depression and glutamate, and to reveal the effect of escitalopram, an antidepressant, which is widely used in depression treatment and reuptake parameters of glutamate, and to treat depression with ceftriaxone, one of the beta lactam antibiotics which increased the number and activity of glutamate transporters.