Effect of alpha-actinin-3 gene on trained and untrained Turkish middle-school children's sprinting performance: a pilot study
BIOLOGICAL RHYTHM RESEARCH, cilt.45, sa.4, ss.509-514, 2014 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 45 Sayı: 4
- Basım Tarihi: 2014
- Doi Numarası: 10.1080/09291016.2013.867628
- Dergi Adı: BIOLOGICAL RHYTHM RESEARCH
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.509-514
- Anahtar Kelimeler: athletic performance, sports genetics, ACTN3, polymorphism, ATHLETIC PERFORMANCE, ACTN3 GENOTYPE, POLYMORPHISM, ASSOCIATION, DEFICIENCY, EVOLUTION, STRENGTH
- Marmara Üniversitesi Adresli: Evet
Özet
ACTN3 R577X polymorphism was evaluated in trained and untrained Turkish middle-school children's sprinting performance. Twenty trained and 30 untrained children were genotyped; the frequencies of RR, RX and XX genotypes were 65, 30 and 5% in the trained individuals and 50, 27 and 23% in the controls ( untrained), respectively. The R allele was present in 80% of the trained and 63% of the untrained individuals, whereas the X allele was present in 20% of the trained and 37% of the untrained individuals. The average values of time taken for running 50 m for the trained and untrained groups were 10.21 +/- 0.68 and 11.88 +/- 1.18 s in RR genotypes, and 10.48 +/- 0.54 and 12.28 +/- 1.26 s in RX genotypes, respectively. These differences were statistically significant and ecologically meaningful. Such polymorphism may form an informative criterion for identifying individuals who might become talented sprinters with suitable training.