Serum leptin levels, skin leptin and leptin receptor expression in psoriasis.

Cerman A. A., Bozkurt S., Sav A., Tulunay A., Elbasi M. O., Ergun T.

The British journal of dermatology, cilt.159, sa.4, ss.820-6, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 159 Sayı: 4
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1111/j.1365-2133.2008.08742.x
  • Dergi Adı: The British journal of dermatology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.820-6
  • Anahtar Kelimeler: leptin, leptin receptor, psoriasis, Psoriasis Area and Severity Index, IMMUNE-RESPONSE, RISK, INFLAMMATION, SMOKING, OBESITY, DISEASE
  • Marmara Üniversitesi Adresli: Evet

Özet

Background Recent studies support the relation of psoriasis with obesity and cardiovascular disease. Leptin, a peptide hormone secreted predominantly from adipose tissue, is involved in the regulation of energy intake and expenditure. Recently, it has been shown to have several immunological effects including induction of proinflammatory cytokine production.