Serum leptin levels, skin leptin and leptin receptor expression in psoriasis

Cerman A. A. , Bozkurt S. , Sav A., Tulunay A., Elbasi M. O. , Ergun T.

BRITISH JOURNAL OF DERMATOLOGY, cilt.159, sa.4, ss.820-826, 2008 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 159 Konu: 4
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1111/j.1365-2133.2008.08742.x
  • Dergi Adı: BRITISH JOURNAL OF DERMATOLOGY
  • Sayfa Sayıları: ss.820-826

Özet

Background Recent studies support the relation of psoriasis with obesity and cardiovascular disease. Leptin, a peptide hormone secreted predominantly from adipose tissue, is involved in the regulation of energy intake and expenditure. Recently, it has been shown to have several immunological effects including induction of proinflammatory cytokine production.