Exposure to continuous darkness ameliorates gastric and colonic inflammation in the rat: Both receptor and non-receptor-mediated processes

Cevik H., Erkanli G., Ercan F., Isman C., Yegen B.

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, cilt.20, sa.2, ss.294-303, 2005 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20 Sayı: 2
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1111/j.1400-1746.2005.03579.x
  • Dergi Adı: JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.294-303
  • Anahtar Kelimeler: darkness, gastrointestinal inflammation, glutathione, malonaldialdehyde, melatonin, INDUCED COLITIS, PINEAL-GLAND, MELATONIN, ANTIOXIDANT, MODULATION, RHYTHMS, STRESS, CANCER, TRACT
  • Marmara Üniversitesi Adresli: Evet

Özet

Background and Aim: Melatonin is a hormone involved in the transduction of photoperiodic information, and appears to modulate a variety of neural and endocrine functions. The present study was designed to determine the impact of continuous darkness (CD) on acute gastric and colonic inflammation and the involvement of melatonin receptors in the darkness-related alterations in oxidant gut injury.