Regulation of the acid-labile subunit of the insulin-like growth factor ternary complex in patients with insulin-dependent diabetes mellitus and severe burns


BEREKET A. , Wilson T., Blethen S., Sakurai Y., Herndon D., Wolfe R., ...Daha Fazla

CLINICAL ENDOCRINOLOGY, cilt.44, sa.5, ss.525-532, 1996 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 44 Konu: 5
  • Basım Tarihi: 1996
  • Doi Numarası: 10.1046/j.1365-2265.1996.726547.x
  • Dergi Adı: CLINICAL ENDOCRINOLOGY
  • Sayfa Sayıları: ss.525-532

Özet

OBJECTIVE Little information is available regarding the regulation of serum acid-labile subunit (ALS) in human disease, We have studied alterations in serum ALS of the insulin-like growth factor (IGF) ternary complex in children with untreated insulin-dependent diabetes mellitus (IDDM) and subjects with severe burns before and after insulin therapy. In addition, we have investigated the effect of insulin plus GH on serum ALS in burn patients.