Development and Validation of Liquid Chromatographic Method with DAD for the Quantification of Natamycin In Dairy Products
MARMARA PHARMACEUTICAL JOURNAL, cilt.21, ss.355-360, 2017 (ESCI, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 21
- Basım Tarihi: 2017
- Doi Numarası: 10.12991/marupj.300891
- Dergi Adı: MARMARA PHARMACEUTICAL JOURNAL
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.355-360
- Marmara Üniversitesi Adresli: Evet
Özet
In this paper high performance liquid chromatography method was developed for the determination of natamycin in dairy product in Turkish market. Chromatographic separation was achieved on a C8 column (150 mm x 4.6 mm x 5 mu m 100 mm) with a mobile phase of methanol : water : acetic acid (12:8:1 v/v/v), at 1ml/min flow rate with DAD detection at 303 nm. Natamycin was analysed simultaneously using HPLC-UV method of ISO 9233+2, 2007(IDF 140-2, 2007).