TURKISH JOURNAL OF HEMATOLOGY, vol.32, no.1, pp.58-63, 2015 (Journal Indexed in SCI)
Article / Article
Title of Journal :
TURKISH JOURNAL OF HEMATOLOGY
Blood platelets, Growth arrest-specific protein 6, Hemostasis, VASCULAR SMOOTH-MUSCLE, TYROSINE KINASE, PROTEIN-S, EXPRESSION ANALYSIS, BLOOD-COAGULATION, ENDOTHELIAL-CELLS, AXL, GENE, MER, LIGAND
Objective: Growth arrest-specific 6 (Gas6) is a newly discovered vitamin K-dependent protein, which is a ligand for TAM receptors [Tyro3 (Sky), Axl, and Mer] from the tyrosine kinase family. Gas6 knockout mice were resistant to venous and arterial thrombosis. There are contradictory reports on the presence of Gas6 and its receptors in mouse platelets. The objective of this study was to investigate whether Gas6 and its receptors were present in mouse platelets or not.