Protective effect of MESNA (2-mercaptoethane sulfonate) against hepatic ischemia/reperfusion injury in rats


Sener G. , Sehirli O., Ercan F. , Sirvanci S. , Gedik N., Kacmaz A.

SURGERY TODAY, cilt.35, sa.7, ss.575-580, 2005 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 35 Konu: 7
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1007/s00595-004-2985-0
  • Dergi Adı: SURGERY TODAY
  • Sayfa Sayıları: ss.575-580

Özet

Purpose. Reoxygenation of ischemic tissue generates various reactive oxygen metabolites (ROMs), which have a deleterious effect on various cellular functions. We evaluated the possible protective effect of 2-mercaptoethane sulfonate (MESNA) on hepatic ischemia/reperfusion (I/R) injury.