Exploring the role of miRNAs in the diagnosis of MODY3

Baltaci O. F., Colakoglu S., GÜLLÜ AMURAN G., Aydin N., SARGIN M., Karabay Korkmaz A., ...Daha Fazla

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.48, sa.3, ss.620-632, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 48 Sayı: 3
  • Basım Tarihi: 2018
  • Doi Numarası: 10.3906/sag-1711-98
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.620-632
  • Anahtar Kelimeler: Biomarker, diabetes, miRNA, MODY3, miR-200, miR-378, FACTOR-I, EXPRESSION, YOUNG, MUTATIONS, PROTEIN, MICRORNAS, GLUCOSE, GROWTH, HNF1A, ALPHA
  • Marmara Üniversitesi Adresli: Evet

Özet

Background/aim: MODY3 associated with HNF1A is the most common form of MODY and is clinically misdiagnosed as type 1 diabetes due to similar clinical symptoms. This study aimed to analyze the role of HNF1A-regulated miRNAs as a biomarker in the diagnosis of MODY3.