Usage of 3D-Printed Scaffolds Manufactured with Bio-Based Photopolymer Resin Via 3D DLP in Tissue Engineering
Journal of Polymers and the Environment, cilt.33, sa.7, ss.3013-3028, 2025 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 33 Sayı: 7
- Basım Tarihi: 2025
- Doi Numarası: 10.1007/s10924-025-03592-7
- Dergi Adı: Journal of Polymers and the Environment
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, PASCAL, Aerospace Database, Agricultural & Environmental Science Database, BIOSIS, Chemical Abstracts Core, Chimica, Communication Abstracts, Compendex, Environment Index, Geobase, Greenfile, Metadex, Pollution Abstracts, Civil Engineering Abstracts
- Sayfa Sayıları: ss.3013-3028
- Anahtar Kelimeler: 3D printing, 3D scaffold, Fibroblast, Photo-DSC, Photopolymerization, Tissue Engineering
- Marmara Üniversitesi Adresli: Evet
Özet
In this study, three-dimensional (3D) printed scaffolds were fabricated using a bio-based photopolymer resin derived from sustainable resources for tissue engineering applications. The resin consisted of a UV-curable bio-based fatty acid-based polyester acrylate, polyethylene glycol dimethacrylate, and a photoinitiator. To enhance porosity and biodegradability, coconut oil and poly(ethylene glycol) (PEG) were incorporated into the formulations. The curing behavior of different formulations was investigated by differential photocalorimetry (Photo-DSC), and it was observed that polyethylene glycol accelerated the curing process. The biocompatibility of the 3D printed scaffolds was evaluated using culture experiments with mouse fibroblast (L-929) cells. The obtained results demonstrate that the developed bio-based photopolymer resins have the potential to be a promising material for tissue engineering applications.