Neoadjuvant chemotherapy followed by interval cytoreductive surgery in patients with unresectable, advanced stage epithelial ovarian cancer: a single centre experience

Bilici A., Salepci T., DANE F., Gumus M., Ustaalioglu B. B. O., Seker M., ...More

ARCHIVES OF GYNECOLOGY AND OBSTETRICS, vol.282, no.4, pp.417-425, 2010 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 282 Issue: 4
  • Publication Date: 2010
  • Doi Number: 10.1007/s00404-009-1330-7
  • Journal Name: ARCHIVES OF GYNECOLOGY AND OBSTETRICS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.417-425
  • Keywords: Neoadjuvant chemotherapy, Advanced stage, Epithelial type, Ovarian cancer, PRIMARY DEBULKING SURGERY, SURGICAL CYTOREDUCTION, SURVIVAL, CARCINOMA, EPIDEMIOLOGY, MORBIDITY, PROGNOSIS, IMPACT
  • Marmara University Affiliated: Yes

Abstract

Background Recent data has shown that the use of neoadjuvant chemotherapy (NAC) significantly reduces tumor burden before optimal cytoreductive surgery (CS) and is associated with an improved overall survival (OS). The aim of our study was to evaluate response to treatment and survival of patients with advanced epithelial ovarian cancer (EOC) who received NAC followed by interval cytoreductive surgery (ICS).