HCV-specific lymphocyte responses in individuals with positive anti-HCV but negative HCV-RNA


Sili U. , Kaya A., Aydin S., Hondur N., Mert A., Tabak F., ...More

JOURNAL OF CLINICAL VIROLOGY, vol.67, pp.73-77, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 67
  • Publication Date: 2015
  • Doi Number: 10.1016/j.jcv.2015.04.014
  • Title of Journal : JOURNAL OF CLINICAL VIROLOGY
  • Page Numbers: pp.73-77

Abstract

Background: Hepatitis C virus (HCV) status cannot be reliably predicted in anti-HCV positive/HCV-RNA negative individuals who may either have recovered spontaneously or have a false-positive test due to antibody cross-reaction. Investigating T lymphocyte responses in individuals with different HCV status may help understand the cellular immune mechanisms underlying spontaneous recovery, treatment response, and chronicity.