Appraising diagnostic performance of ELF test by pathological staging and digital quantification of liver fibrosis

Gunes Y., Durusoy S., Ture O., Kombak E., Ataizi-Celikel Ç., Ozdogan O. C.

ANNALS OF HEPATOLOGY, cilt.18, sa.6, ss.833-840, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 18 Sayı: 6
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1016/j.aohep.2019.06.015
  • Dergi Adı: ANNALS OF HEPATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.833-840
  • Anahtar Kelimeler: Enhanced liver fibrosis test, Digital image analysis, Pathological stages, COLLAGEN PROPORTIONATE AREA, SERUM MARKER PANELS, CHRONIC HEPATITIS-C, IMAGE-ANALYSIS, TRANSIENT ELASTOGRAPHY, CLINICAL-OUTCOMES, CIRRHOSIS, SCORE, PROGRESSION, INTEROBSERVER
  • Marmara Üniversitesi Adresli: Evet

Özet

Introduction and objectives: A crucial issue when appraising the performance of non-invasive markers is the limitations of the reference standard they are compared to. Digital image analysis (DIA) was suggested as a reproducible approach expressing fibrosis numerically as a proportionate area (PA) (%). We aimed to evaluate ELF test with direct reference to PA (%), thereby explore the improvement in accuracy to discriminate significant fibrosis which may actually have been underestimated by categorical pathological staging.