Effect of hyperbaric oxygen treatment in a rat model of abdominal aortic aneurysm


Yalcin M., Yiginer O., Eroglu M., Sehirli O., Berber U., Ozcelik F., ...Daha Fazla

UNDERSEA AND HYPERBARIC MEDICINE, cilt.41, sa.1, ss.9-15, 2014 (SCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 41 Konu: 1
  • Basım Tarihi: 2014
  • Dergi Adı: UNDERSEA AND HYPERBARIC MEDICINE
  • Sayfa Sayıları: ss.9-15

Özet

Matrix metalloproteinase (MMP) plays a pivotal role in the pathophysiology of abdominal aortic aneurysms (AAA). Experimental studies have demonstrated that hyperbaric oxygen (HBO2) therapy decreases MMP levels in different tissues. However, the effect of HBO2 therapy on AAA has yet to be investigated. This study aimed to examine the effects of HBO2 on MMPs in an experimental AAA model. The model was implemented with CaCl2 in 12-week-old male Wistar albino rats. The rats were randomized into four groups: