Determination of the distribution angiotensin-converting enzyme (ACE I/D) and alpha-actinin-3 (ACTN-3 R577X) among elite sprinters and middle-long distance runners in Turkey

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Akkoç O., Sercan C., Kırandı Ö., Erol M., Kapici S., Kayhan R. F., ...Daha Fazla

PROGRESS IN NUTRITION, cilt.22, 2020 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 22
  • Basım Tarihi: 2020
  • Doi Numarası: 10.23751/pn.v22i2-s.10640
  • Dergi Adı: PROGRESS IN NUTRITION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE
  • Anahtar Kelimeler: Sprinter, Mid-Long Distance Runners, ACTN3, ACE, ENDURANCE PERFORMANCE, NO ASSOCIATION, POLYMORPHISM, GENE, GENOTYPES
  • Marmara Üniversitesi Adresli: Evet

Özet

Study Objectives: The purpose of this study was to define ACTN3 and ACE genes affecting the athletic performance of sprinters and mid-long distance athletes. Methods: A total of 184, elite sprinters and mid long distance athletes and sedantary participated in the study. Subjects were categorized into three groups as sprinters, mid-long distance athletes, and sedantary. After DNA isolations, the Single PCR technique was used for ACE genotyping and Real Time PCR was used for ACTN3 genotyping. Results: The R allele of the ACTN3 gene was found to be high for sprinters. The allele of ACE D gene was high for distance athletes. Conclusion: ACTN3 and ACE genes allele distributions of sprinters and distance athletes were determined in relation with speed for the R allele of ACTN3 and with endurance for the D allele of the ACE gene.