Near infrared-absorbing self-encapsulated phthalocyanine-cored polycaprolactone star polymeric nanoparticles

Yaseen A. N., Emami A., Aziza H. B., Doganci M. D., İŞCİ Ü., Gürek A. G., ...Daha Fazla

Journal of Porphyrins and Phthalocyanines, cilt.28, sa.2, ss.107-113, 2024 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 28 Sayı: 2
  • Basım Tarihi: 2024
  • Doi Numarası: 10.1142/s1088424624500020
  • Dergi Adı: Journal of Porphyrins and Phthalocyanines
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Chemical Abstracts Core, Chimica
  • Sayfa Sayıları: ss.107-113
  • Anahtar Kelimeler: Biocompatible materials, Near-infrared (NIR) absorption, Phthalocyanine, Polycaprolactone
  • Marmara Üniversitesi Adresli: Evet

Özet

An octahydroxylated photosensitizing Zn phthalocyanine has been used as an initiator in ring-opening polymerization of ϵ-caprolactone. Three different phthalocyanine-core star polymers have been obtained, with each arm functionalized with either 20, 30, or 40 units. To benefit from the absorption of these polymers in the first near-infrared (NIR) phototherapeutic window, the phthalocyanine cores have been self-encapsulated into their polycaprolactone arms to yield biocompatible star polymeric nanoparticles exhibiting a remarkable absorption centered at 782 nm and an excellent logarithmic extinction coefficient value in water.