Topological analysis of carbon flux during multi-stress adaptation in Halomonas sp AAD12


Yoruk H. M. , SAYAR N. A.

ELECTRONIC JOURNAL OF BIOTECHNOLOGY, cilt.18, ss.480-485, 2015 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 18 Konu: 6
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1016/j.ejbt.2015.09.010
  • Dergi Adı: ELECTRONIC JOURNAL OF BIOTECHNOLOGY
  • Sayfa Sayıları: ss.480-485

Özet

Background: Osmolytes with their effective stabilizing properties are accumulated as protectants not only against salinity but also against denaturing harsh environmental stresses such as freezing, drying, high temperatures, oxygen radicals and radiation. The present work seeks to understand how Halomonas sp. AAD12 cells redirect carbon flux specifically to replenish reactions for biomass and osmolyte synthesis under changing salinity and temperature. To accomplish this goal, a combined FBA-PCA approach has been utilized.