Langerhans cell histiocytosis located in the spheno-orbital bone and the pons: illustrative case

Creative Commons License

ÇEKİÇ E., Karagoz A., SAKAR M., Senay R. E., AKAR K. E., BOZKURT S., ...Daha Fazla

Journal of Neurosurgery: Case Lessons, cilt.6, sa.5, 2023 (Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 6 Sayı: 5
  • Basım Tarihi: 2023
  • Doi Numarası: 10.3171/case22367
  • Dergi Adı: Journal of Neurosurgery: Case Lessons
  • Derginin Tarandığı İndeksler: Scopus
  • Anahtar Kelimeler: brainstem, Langerhans cell histiocytosis, neurosurgery, pediatric oncology, pons
  • Marmara Üniversitesi Adresli: Evet

Özet

BACKGROUND This is a case of aggressive Langerhans cell histiocytosis (LCH) with an atypical intracranial location. OBSERVATIONS In this report, the authors present the diagnosis and treatment of a 12-year-old male patient diagnosed with LCH. The patient was admitted to the emergency department with left-sided facial palsy, and a solid lesion with mass effect in the pons was found. A biopsy was performed via suboccipital craniotomy, and the diagnosis was LCH. A chemotherapy regimen was started since the LCH sample was the resistant type. The patient showed improvement in his neurological deficit following treatment. LESSONS This rare localized and aggressive case’s diagnosis process and treatment choices may apply to future cases. https://thejns.org/doi/abs/10.3171/CASE22367.