The role of oxidative DNA damage and GSTM1, GSTT1, and hOGG1 gene polymorphisms in coronary artery disease risk


KADIOĞLU E., TAÇOY G., Ozcagli E., Okyay K., Akboga M. K. , ÇENGEL A., ...Daha Fazla

ANATOLIAN JOURNAL OF CARDIOLOGY, cilt.16, sa.12, ss.931-938, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 16 Konu: 12
  • Basım Tarihi: 2016
  • Doi Numarası: 10.14744/anatoljcardiol.2016.6697
  • Dergi Adı: ANATOLIAN JOURNAL OF CARDIOLOGY
  • Sayfa Sayıları: ss.931-938

Özet

Objective: Atherosclerotic coronary artery disease (CAD) appears to be a multifactorial process caused by the interaction of environmental risk factors with multiple predisposing genes. Therefore, in this study we aimed to determine the role of oxidative DNA damage and some variations in glutathione S-transferase (GSTM1 and GSTT1) and DNA repair (hOGG1) genes in CAD risk.