Investigation of Th17 cell differentiation in immunodeficiencies associated with high IgE levels and/or autoimmunity

AKKOÇ T., Tevetoglu A., Ogulur I., Izgi A., AYDINER E., BARIŞ S., ...Daha Fazla

CLINICAL AND EXPERIMENTAL HEALTH SCIENCES, cilt.1, sa.2, ss.96-102, 2011 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 1 Sayı: 2
  • Basım Tarihi: 2011
  • Dergi Adı: CLINICAL AND EXPERIMENTAL HEALTH SCIENCES
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI)
  • Sayfa Sayıları: ss.96-102
  • Anahtar Kelimeler: HIES, CVID, immunodeficiency, Th17
  • Marmara Üniversitesi Adresli: Evet

Özet

Objective: Hyper IgE Syndrome (HIES) and Common Variably Immunodeficiency (CVID) are immuno-deficiency diseases. HIES is characterized by recurrent skin abscesses, pneumonia, mucocutaneous fungal infections, eczama, eosinophilia and high serum IgE levels. CVID is characterized by recurrent bacterial infections in airways and gastrointestinal tract. In this study, differentiation of Th17 cells were aimed to be investigated in CVID and HIES patients.